| # | Title | Orignal Air Date |
| 01. | Pilot | Tuesday November 16th, 2004 |
| A young kindergarten teacher, Rachel Adler, who suffers from seizures collapses in her classroom after uncontrolled gibberish slips out her mouth while she is about to teach her students. She is taken to Dr, House and his team of experts who identify it might be a tumor, and she might have only a week to live. | ||
| 02. | Paternity | Tuesday November 23rd, 2004 |
| When a teenage lacrosse player is stricken with an unidentifiable brain disease, Dr. House and the team hustle to give his parents answers. Chase breaks the bad news, the kid has MS, but the boy’s night-terror hallucinations disprove the diagnosis and send House and his team back to square one. As the boy’s health deteriorates, House’s side-bet on the paternity of the patient infuriates Dr. Cuddy and the teenager’s parents, but may just pay off in spades. | ||
| 03. | Occam’s Razor | Tuesday November 30th, 2004 |
| 04. | Maternity | Tuesday December 7th, 2004 |
| 05. | Damned If You Do | Tuesday December 14th, 2004 |
| When a nun comes into the clinic with swollen arms, a rash and bleeding in her palms, Dr. House’s diagnosis is a bad allergy, not stigmata. However, when he gives her a shot of medication, she has a heart attack, and whether he gave her the correct amount of medicine comes into question. As the nun’s case unfolds, the team has to deal with questions regarding their own calling, faith and whether or not they can trust the direction in which their mentor is leading them. | ||
| 06. | Socratic Method | Tuesday December 21st, 2004 |
| When it appears that Lucy Palermo, a schizophrenic mom with deadly deep vein thrombosis, is lying about her alcohol intake, Dr. House is the lone voice of reason. Under the scrutiny of her hyper-vigilant teenage son, House takes Lucy off all her medication and secretly sends Foreman and Chase to search her apartment for clues. An anonymous call to Social Services makes House question whether Lucy is really schizophrenic, and causes Lucy’s son, Lucas, to blame Dr. House for making the call. Wading through Lucy’s altered reality to get to the truth and save her life, House discovers it isn’t mom who’s keeping the secrets and reality isn’t always what it seems. | ||
| 07. | Fidelity | Tuesday December 28th, 2004 |
| When a young housewife falls ill, House suspects that she has contracted a rare sexually transmitted disease, but she and her husband each deny having an affair. | ||
| 08. | Poison | Tuesday January 25th, 2005 |
| House and his team investigate the mysterious poisoning of a high-school student, and they think they have the answers they need until a second teen develops the same symptoms. | ||
| 09. | DNR | Tuesday February 1st, 2005 |
| 10. | Histories | Tuesday February 8th, 2005 |
| 11. | Detox | Tuesday February 15th, 2005 |
| While trying to figure out why a young patient won’t stop bleeding, House takes Cuddy’s challenge and goes off Vicodin for a week in exchange for no clinic duty for a month. If House and his team can’t determine the source of his patient’s blood loss, the 16-year-old car accident victim will die in a matter of days. As House’s withdrawal symptoms become more and more severe, his directives for his patient are more harsh and risky than usual, forcing Foreman and Cameron to fear he may not be thinking clearly enough to save the patient’s life. | ||
| 12. | Cursed | Tuesday February 22nd, 2005 |
| A 12-year-old boy believes he’s cursed after a Ouija board tells him he’s going to die. His father, a major financial supporter of the hospital, makes escalating demands of House and the team as they try to diagnose the boy’s pneumonia-like symptoms and incongruous rash. Tension intensifies when House invites Chase’s estranged father, a renowned doctor visiting from Australia, into their circle of diagnosticians – much to Chase’s discomfort – and House is intrigued by Chase’s lack of relationship with his father. When the boy’s diagnosis becomes more evident, the young patient is forced to face the idea that his father may not be everything he believes. | ||
| 13. | Sports Medicine | Tuesday March 1st, 2005 |
| A severely broken arm reveals a bizarre case of bone loss and ends the comeback plans of major league pitcher Hank Wiggen (guest star Scott Foley). House suspects Hank - with a history of drug abuse - is lying about using steroids, as his condition worsens. When Hank’s kidneys start to fail, his wife offers to donate hers, but she would have to abort her early pregnancy. Forced into an impossible solution, and admitting failure as an addict, Hank tries to take his own life. House and his team must isolate and fix the problem soon if this pitcher’s life, as well his career, can be saved. | ||
| 14. | Cursed | Tuesday March 1st, 2005 |
| 15. | Control | Tuesday March 15th, 2005 |
| 16. | Mob Rules | Tuesday March 22nd, 2005 |
| 17. | Heavy | Tuesday March 29th, 2005 |
| 18. | Role Model | Tuesday April 12th, 2005 |
| 19. | Babies & Bathwater | Tuesday April 19th, 2005 |
| While House and his team scramble to discover what’s causing brain and kidney dysfunction in a pregnant woman, Vogler (guest star Chi McBride) is on the warpath to get House fired. House diagnoses his pregnant patient’s illness, but now she and her husband struggle with an emotional and heartbreaking choice: to save her life, or that of her unborn child. Meanwhile, Vogler sets up a board meeting to get rid of House, but when Wilson objects, Vogler lashes out against him and shocks Cuddy and the rest of the board with his decision. Finally, Cuddy takes a stand against Vogler. | ||
| 20. | Kids | Tuesday May 3rd, 2005 |
| While a meningitis scare overwhelms the resources and staff of Princeton-Plainsboro Teaching Hospital, House zeros in on a single patient: a 12-year-old whose symptoms are similar to, but not quite right for, meningitis. Cuddy gives them an hour to crack the case before pulling their medical manpower to treat the countless patients taking over the waiting rooms, but when they discover something quite unexpected, House, Foreman and Chase must devise ingenious ways and locations to treat the girl’s delicate condition amid the chaos. Meanwhile, House asks Cameron to come back to her job now that Vogler is gone, but she’s got a surprising requirement. | ||
| 21. | Love Hurts | Tuesday May 10th, 2005 |
| While Princeton-Plainsboro Hospital is rife with rumor and speculation about House’s imminent date with Cameron, House apparently scares a meek clinic patient into having a stroke. The team must navigate their way through the patient’s odd proclivities, overbearing “friend” and reluctant parents in order to stop the strokes and try to save the guy’s life. All the while, Wilson, Cuddy and the team offer House dating advice and lay odds on the outcome. | ||
| 22. | Three Stories | Tuesday May 17th, 2005 |
| House’s ex-girlfriend Stacy Warner (guest star Sela Ward) returns - not to be with House, but to get his help for her ailing husband. While House decides whether or not to take the case, Cuddy instructs him to substitute for a sick professor and present a lecture to a class of medical students. As he weaves the stories of three patients (including guest star Carmen Electra) who all present with a similar symptom, House gives a lecture the students will never forget. In the end, they come out with a broader understanding of diagnostics and House’s team comes out with a greater understanding of him. | ||
| 23. | The Honeymoon | Tuesday May 24th, 2005 |
| House insists he can handle things when Stacy (guest-star Sela Ward), the woman he once loved, asks him to diagnose Mark, the man she married. When Mark’s tests come back normal yet symptoms show that his brain is dying, the puzzle may be one that even House can’t solve. While Wilson worries about House’s emotional well-being, the team is blown away by his over-the-top demands. As House struggles to put his emotions aside and solve the case, Cuddy adds to his dilemma and offers Stacy a reason to stay.
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Season 1
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